SimilOss® was created on the observation that the appropriate microstructure is essential for a synthetic bone graft. This observation has been scientifically substantiated since Orthogem first made its observation in 2001.

(Interconnected porous Hydroxyapatite for ceramics for bone tissue engineering, Dec 2008 (Osteoinductive Biomaterials: Current knowledge of properties, experimental models and biological mechanisms; Habibovic et al; European Cells Materials Vol. 21 2011 (pages 407 – 429))).


Other synthetic Bone Grafts produce a microstructure which, although similar in appearance to cancellous bone, simply does not produce the appropriate environment for bone regeneration. Orthogem refined the basic microstructure to ensure a consistent implant performance.
 

Structure of SimilOss® 

The highly porous structure of SimilOss® results in:

  • Accommodates osteocyte formation within the graft site
  • Recruits and actively conducts osteogenic cells throughout the graft micro-structural ‘superconduction’
  • Osteocyte manipulation stimulates natural bone formation
  • Total resorbtion of the ceramic Synthetic Bone Graft
  • No compromise in graft site strength or viability
  • ‘Fit and Forget’
  
     

The proprietary manufacturing process delivers a fully resorbable structure, engineered with three distinct pore sizes to restore the naturally intended osteocyte density and promotion of cell seeding.

Clinical evaluation of SimilOss®

The use of SimilOss® in a number of spinal indications has reinforced the performance demonstrated in pre-clinical studies.

Case 1

Transforaminal Lumbar Interbody Fusion at L5/S1 in 38 year old

         
3 months post-op 6 months post-op 12 months post-op 

 

Case 2

 Postero-Lateral Spinal Fusion at L4/S1 in 62 year old female

   
     
 3 months post-op  6 months post-op  12 months post-op

 

Advantages of SimilOss® Synthetic Bone Graft

  • Superior porous structural design confirmed through extensive pre-clinical testing1
  • Super conduction guides bone growth throughout the whole implant site with homogeneous osteocyte density
  • Resorbed at the same rate as new bone formation, fully integrated with the host’s bone remodelling process
  • Only CE mark Class III device made from pure hydroxyapatite that is fully resorbable, resorption is controlled by the bone remodelling process not by its chemical composition
  • Excellent clinical results2
  • Reliable and consistent performance